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TOP 30 Papers Downloaded in 2021

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Article

[1] 2,178 Chang-Wan Han, Eun-Joo Lee, Tsutomu Iwaya, Hitomi Kataoka and Masahiro Kohzuki. “Development of the Korean Version of Short-Form 36-Item Health Survey: Health Related QOL of Healthy Elderly People and Elderly Patients in Korea.” (2004) Jul. 203 (3) 189-194.
[2] 2,161 Masao Sato and Masuo Kondoh. “Recent Studies on Metallothionein: Protection Against Toxicity of Heavy Metals and Oxygen Free Radicals.” (2002) Jan. 196 (1) 9-22. [Review]
[3] 1,765 Leonard P Rybak, Debashree Mukherjea, Sarvesh Jajoo and Vickram Ramkumar. “Cisplatin Ototoxicity and Protection: Clinical and Experimental Studies.” (2009) Nov. 219 (3) 177-186. [Invited Review for the 90th Anniversary]
[4] 1,369 Kazumichi Furuyama, Kiriko Kaneko and Patrick D. Vargas V. “Heme as a Magnificent Molecule with Multiple Missions: Heme Determines Its Own Fate and Governs Cellular Homeostasis.” (2007) Sep. 213 (1) 1-16. [Invited Review]
[5] 1,333 Xuan Hong, Baohong Cui, Meng Wang, Zhaoyang Yang, Li Wang and Qingyong Xu. “Systemic Immune-inflammation Index, Based on Platelet Counts and Neutrophil-Lymphocyte Ratio, Is Useful for Predicting Prognosis in Small Cell Lung Cancer.” (2015) Aug. 236 (4) 297-304.
[6] 1,246 Tadashi Terada and Masaharu Kawaguchi. “Primary Clear Cell Adenocarcinoma of the Peritoneum.” (2005) Jul. 206 (3) 271-275. [Case]
[7] 1,192 Toshiyuki Takahashi, Kazuo Fujihara, Ichiro Nakashima, Tatsuro Misu, Isabelle Miyazawa, Masashi Nakamura, Shohei Watanabe, Naoto Ishii and Yasuto Itoyama. “Establishment of a New Sensitive Assay for Anti-Human Aquaporin-4 Antibody in Neuromyelitis Optica.” (2006) Dec. 210 (4) 307-313.
[8] 1,191 Shigeki Shibahara. “The Heme Oxygenase Dilemma in Cellular Homeostasis: New Insights for the Feedback Regulation of Heme Catabolism.” (2003) Aug. 200 (4) 167-186. [Invited Review]
[9] 1,115 Akira Yasutake, Miyuki Matsumoto, Masako Yamaguchi and Noriyuki Hachiya. “Current Hair Mercury Levels in Japanese: Survey in Five Districts.” (2003) Mar. 199 (3) 161-169.
[10] 1,066 Ki Hun Cho, Kyoung Jin Lee and Chang Ho Song. “Virtual-Reality Balance Training with a Video-Game System Improves Dynamic Balance in Chronic Stroke Patients.” (2012) Sep. 228 (1) 69-74.
[11] 1,046 Yihe Jin, Norimitsu Saito, Kouji H. Harada, Kayoko Inoue and Akio Koizumi. “Historical Trends in Human Serum Levels of Perfluorooctanoate and Perfluorooctane Sulfonate in Shenyang, China.” (2007) May 212 (1) 63-70.
[12] 983 Duygu Gezen-Ak, Erdinç Dursun, Turan Ertan, Hasmet Hanagasi, Hakan Gürvit, Murat Emre, Engin Eker, Melek Öztürk, Funda Engin and Selma Yilmazer. “Association between Vitamin D Receptor Gene Polymorphism and Alzheimer's Disease.” (2007) Jul. 212 (3) 275-282.
[13] 974 Tae Hyung Kim, Sang-Heon Kim, Ji-Young Seo, Hana Chung, Hyun Jung Kwak, Sang-Kyung Lee, Ho Joo Yoon, Dong Ho Shin, Sung Soo Park and Jang Won Sohn. “Blockade of the Wnt/β-Catenin Pathway Attenuates Bleomycin-Induced Pulmonary Fibrosis.” (2011) Jan. 223 (1) 45-54.
[14] 972 Seiichiro Nagai, Tadashi Mabuchi, Shuji Hirata, Tomoko Shoda, Tsuyoshi Kasai, Sadaki Yokota, Hiroshi Shitara, Hiromichi Yonekawa and Kazuhiko Hoshi. “Correlation of Abnormal Mitochondrial Distribution in Mouse Oocytes with Reduced Developmental Competence.” (2006) Oct. 210 (2) 137-144.
[15] 946 Chiho Watanabe. “Modification of Mercury Toxicity by Selenium: Practical Importance?” (2002) Feb. 196 (2) 71-77. [Review]
[16] 936 Susumu Ogawa, Mikihito Ishiki, Kazuhiro Nako, Masashi Okamura, Miho Senda, Takefumi Mori and Sadayoshi Ito. “Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, Decreases Systolic Blood Pressure in Japanese Hypertensive Patients with Type 2 Diabetes.” (2011) Feb. 223 (2) 133-135.
[17] 932 Shigeru Taketani. “Aquisition, Mobilization and Utilization of Cellular Iron and Heme: Endless Findings and Growing Evidence of Tight Regulation.” (2005) Apr. 205 (4) 297-318. [Invited Review]
[18] 858 Mehmet Kanter, Ismail Meral, Zabit Yener, Hanefi Ozbek and Halit Demir. “Partial Regeneration/Proliferation of the β-Cells in the Islets of Langerhans by Nigella sativa L. in Streptozotocin-Induced Diabetic Rats.” (2003) Dec. 201 (4) 213-219.
[19] 844 Soisungwan Satarug, Muneko Nishijo, Jerome M. Lasker, Robert J. Edwards and Michael R. Moore. “Kidney Dysfunction and Hypertension: Role for Cadmium, P450 and Heme Oxygenases?” (2006) Mar. 208 (3) 179-202. [Invited Review]
[20] 839 Yoshifumi Tsuchiya, Daisuke Ando, Kazushige Goto, Masataka Kiuchi, Mitsuya Yamakita and Katsuhiro Koyama. “High-Intensity Exercise Causes Greater Irisin Response Compared with Low-Intensity Exercise under Similar Energy Consumption.” (2014) Jun. 233 (2) 135-140.
[21] 793 Toshihiro Iwasaki, Naoto Shiba, Hiroo Matsuse, Takeshi Nago, Yuichi Umezu, Yoshihiko Tagawa, Kensei Nagata and Jeffrey R. Basford. “Improvement in Knee Extension Strength through Training by Means of Combined Electrical Stimulation and Voluntary Muscle Contraction.” (2006) May 209 (1) 33-40.
[22] 792 Yuji Owada. “Fatty Acid Binding Protein: Localization and Functional Significance in the Brain.” (2008) Mar. 214 (3) 213-220. [Review]
[23] 791 Ali Cetinkaya, Ertan Bulbuloglu, Ergul Belge Kurutas, Harun Ciralik, Bulent Kantarceken and Mehmet Akif Buyukbese. “Beneficial Effects of N-Acetylcysteine on Acetic Acid-Induced Colitis in Rats.” (2005) Jun. 206 (2) 131-139.
[24] 790 Kazuhiko Igarashi and Miki Watanabe-Matsui. “Wearing Red for Signaling: The Heme-Bach Axis in Heme Metabolism, Oxidative Stress Response and Iron Immunology.” (2014) Apr. 232 (4) 229-253. [Invited Review]
[25] 788 Yuhong Wang, Rie Takai, Hidekatsu Yoshioka and Komei Shirabe. “Characterization and Expression of Serotonin Transporter Genes in Zebrafish.” (2006) Mar. 208 (3) 267-274.
[26] 787 Shiun Dong Hsieh and Hideyo Yoshinaga. “Do People with Similar Waist Circumference Share Similar Health Risks Irrespective of Height?” (1999) May 188 (1) 55-60.
[27] 786 Jin Shijie, Hideyuki Takeuchi, Izumi Yawata, Yohei Harada, Yoshifumi Sonobe, Yukiko Doi, Jianfeng Liang, Li Hua, Satoko Yasuoka, Yan Zhou, Mariko Noda, Jun Kawanokuchi, Tetsuya Mizuno and Akio Suzumura. “Blockade of Glutamate Release from Microglia Attenuates Experimental Autoimmune Encephalomyelitis in Mice.” (2009) Feb. 217 (2) 87-92.
[28] 768 Tatsuro Misu, Kazuo Fujihara, Masashi Nakamura, Kazuhiro Murakami, Minoru Endo, Hidehiko Konno and Yasuto Itoyama. “Loss of Aquaporin-4 in Active Perivascular Lesions in Neuromyelitis Optica: A Case Report.” (2006) Jul. 209 (3) 269-275. [Case]
[29] 765 Kunihiko Nakai, Keita Suzuki, Tomoko Oka, Katsuyuki Murata, Mineshi Sakamoto, Kunihiro Okamura, Toru Hosokawa, Takeo Sakai, Tomoyuki Nakamura, Yoshinori Saito, Naoyuki Kurokawa, Satomi Kame and, Hiroshi Satoh. “The Tohoku Study of Child Development: A Cohort Study of Effects of Perinatal Exposures to Methylmercury and Environmentally Persistent Organic Pollutants on Neurobehavioral Development in Japanese Children.” (2004) Mar. 202 (3) 227-237.
[30] 757 Akemi Ishigaki, Hikari Higashi, Takako Sakamoto and Shigeki Shibahara. “The Great East-Japan Earthquake and Devastating Tsunami: An Update and Lessons from the Past Great Earthquakes in Japan since 1923.” (2013) Apr. 229 (4) 287-299. [Perspective]



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